Hepatosplenic candidiasis in acute leukemia patients

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منابع مشابه

Hepatosplenic candidiasis in patients with acute leukaemia.

A retrospective study of 23 patients with acute leukaemia and hepatosplenic candidiasis (HSC) was conducted to evaluate clinical treatment characteristics in terms of amount and duration of antifungal agents and to assess treatment outcome. Patients were admitted to two major tertiary care centres between 1990 and 1998. The diagnosis of HSC was based on clinical, blood cultures, histologic and ...

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Hepatosplenic candidiasis complicating acute myeloid leukaemia.

A 33-year-old man with acute myeloid leukaemia developed neutropenic fever after induction chemotherapy with cytarabine and daunorubicin. The first blood culture was positive for Escherichia coli and the patient was treated with imipenem (500 mg every 6 hours intravenously [IV]). However, the fever persisted and liver function tests were deranged; alkaline phosphatase (ALP) was 166 U/L (referen...

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Successful initial treatment with caspofungin alone for hepatosplenic candidiasis in a patient with acute myeloblastic leukemia.

C disseminated candidiasis or Hepatosplenic candidiasis (HSC) is a rare and potentially morbid and mortal complication encountered in febrile neutropenic patients. It is generally associated with recovery from neutropenia, and may occur after the treatment of an episode of acute hematogenous candidiasis. Clinical signs and symptoms include fever unresponsive to antibiotics, abdominal pain and t...

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Hepatosplenic fungal infection in adult patients with acute leukemia.

BACKGROUND Hepatosplenic fungal infection is an important infectious complication in adult patients with acute leukemia. METHODS From 2001 to 2004, 163 adult patients were diagnosed with acute leukemia at our center: 41 patients had acute lymphoblastic leukemia (ALL) and 122 patients had acute myeloid leukemia (AML). Their charts were retrospectively reviewed. RESULTS Of these 163 patients,...

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Hepatosplenic candidiasis--a contraindication to marrow transplantation?

To determine whether a prior history of hepatosplenic candidiasis resulted in increased Candida-associated morbidity and mortality after marrow transplant, 15 consecutive patients with biopsy-proven hepatosplenic candidiasis were observed prospectively. All patients received amphotericin B before transplant. Amphotericin B was continued at a dose of 0.5 mg/kg/day from conditioning through marro...

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ژورنال

عنوان ژورنال: Srpski arhiv za celokupno lekarstvo

سال: 2008

ISSN: 0370-8179,2406-0895

DOI: 10.2298/sarh0808414r